abstract：OBJECTIVE:Metabolic syndrome (MetS) can be induced by the oxidative stress conditions caused by ingestion of large amounts of fructose. We investigated the possible protective effects of melatonin administration on liver tissues in fructose-fed rats. MATERIALS AND METHODS:Thirty-two rats were randomly divided into fou...

journal_title：European review for medical and pharmacological sciences

authors： Demirtas CY,Pasaoglu OT,Bircan FS,Kantar S,Turkozkan N

更新日期：2015-05-01 00:00:00

abstract：OBJECTIVE:A combination of comparative analysis of gene expression profiles between normal tissue samples and small cell lung cancer (SCLC) samples and network analysis was performed to identify key genes in SCLC. MATERIALS AND METHODS:Microarray data set GSE43346 was downloaded from Gene Expression Omnibus (GEO), inc...

journal_title：European review for medical and pharmacological sciences

authors： Tantai JC,Pan XF,Zhao H

更新日期：2015-04-01 00:00:00

abstract：OBJECTIVE:In healthy persons, cardiovascular risk is the result of multiple interacting risk associates including demographic, clinical, genetic and environmental factors. Several non-invasive tools such as echocardiography, ultrasonography and electrocardiography as well as new biochemical markers were shown to be app...

journal_title：European review for medical and pharmacological sciences

authors： Albayrak S,Ozhan H,Aslantas Y,Ekinozu I,Tibilli H,Kayapinar O,Melen Study Investigators.

更新日期：2015-04-01 00:00:00

abstract：:Cardiovascular diseases remain one of the major health problems worldwide. The worldwide research against cardio-vascular diseases as well as genome wide association studies were successful in indentifying the loci associated with these prominent life threatening diseases but still a substantial amount of casualty rem...

journal_title：European review for medical and pharmacological sciences

authors： Fu DG

更新日期：2015-04-01 00:00:00

abstract：OBJECTIVE:Intrauterine glucocorticoid (GC) exposure is associated with disturbances in feto-placental growth. This study aimed to investigate whether folic acid supplementation can prevent dexamethasone (Dex)-induced feto-placental growth restriction. MATERIALS AND METHODS:Female C57BL/6J mice were subject to four dif...

journal_title：European review for medical and pharmacological sciences

authors： Zhang A,Zhou LF,Xiang XL,Wang K,Zhou Q,Duan T

更新日期：2015-04-01 00:00:00

abstract：OBJECTIVE:The application of quantitative EEG (δ+θ/α+β value) and GCS value to evaluate the role of music therapy for traumatic brain injury coma patients. PATIENTS AND METHODS:Forty patients of traumatic brain injury coma were selected to meet the inclusion criteria. Twenty cases were selected for the rehabilitation,...

journal_title：European review for medical and pharmacological sciences

authors： Sun J,Chen W

更新日期：2015-04-01 00:00:00

abstract：OBJECTIVE:Post-tonsillectomy pain is believed to be mediated by noxious stimulation of C-fiber afferents located in the peritonsillary space, and local anesthetic infiltration to this area may decrease pain by blocking the sensory pathways and thus preventing the nociceptive impulses. We aimed to compare the effects of...

journal_title：European review for medical and pharmacological sciences

authors： Cakar Turhan KS,Salviz EA,Beton S,Timuroglu ST,Catav S,Ozatamer O

更新日期：2015-04-01 00:00:00

abstract：OBJECTIVE:To analyze serum biomarkers of CVD in selected patients with primary axial reflux of great saphenous vein in one or both lower limbs. PATIENTS AND METHODS:Ninety-six patients affected by uncomplicated varicose veins, were enrolled in the study. A unilateral, primary axial reflux in great saphenous veins was ...

journal_title：European review for medical and pharmacological sciences

authors： Flore R,Ponziani FR,Gerardino L,Santoliquido A,Di Giorgio A,Lupascu A,Nesci A,Tondi P

更新日期：2015-02-01 00:00:00

abstract：OBJECTIVE:Menin, encoded by the Men1 gene, is responsible for β-cell tumor formation in patients with multiple endocrine neoplasia type 1. Recently, Menin has been proven to negatively regulate β-cell proliferation in several mouse models, including hyperglycemia. However, it is unclear how glucose regulates Menin expr...

journal_title：European review for medical and pharmacological sciences

authors： Lu Y,Fei XQ,Yang SF,Xu BK,Li YY

更新日期：2015-02-01 00:00:00

abstract：:From a dermatological aspect, it posed a considerable challenge the skin-limited form of mastocytosis, urticaria pigmentosa and indolent systemic mastocytosis (ISM) with cutaneous lesions. Despite the favourable prognosis, lifelong dermatological control is needed, during which the average symptomatic therapy does not...

journal_title：European review for medical and pharmacological sciences

authors： Marton I,Pósfai É,Borbényi Z,Bödör C,Papp G,Demeter J,Korom I,Varga E,Bata-Csörgő Z

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVE:Obesity has been associated with hypothyroidism and cardiac autonomic dysfunction. The present study aimed to investigate whether cardiac autonomic dysfunction in young obese males might be related to an underlying thyroid disturbance. PATIENTS AND METHODS:On the basis of body mass index (BMI), 40 participan...

journal_title：European review for medical and pharmacological sciences

authors： Al-Trad BA,Faris MA,Al-Smadi M,Bashir A,Mansi M,Alaraj M,Al-Hazimi A

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVE:Osteoradionecrosis (ORN) is a bone aseptic necrosis which develops on post-irradiated bone tissue of patients who underwent radiotherapy for head-neck tumors. The mandible presents a higher risk to develop ORN, if compared to the maxillary bone, due to its lower vascularization. The aim of the present study i...

journal_title：European review for medical and pharmacological sciences

authors： Manzon L,Rossi E,Fratto G

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to improve the understanding of FBA in children and to decrease the rate of misdiagnosis, missed diagnosis and morbidity. PATIENTS AND METHODS:We analyzed the clinical features and the three-dimensional reconstructed CT images of 590 children with foreign body aspiration (FBA) in th...

journal_title：European review for medical and pharmacological sciences

authors： Yang C,Hua R,Xu K,Hua X,Ma P,Zheng JN,Li SD,Li JS,Rong YT,Hu CF,Lu X,Ma H,Chen GH,Quan Q

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVE:This paper aims to investigate the interaction mechanism between pioglitazone/simvastatin and the CD40-CD40 ligand (CD40-CD40L) system and to determine their interaction effects on atherosclerosis in rabbits. MATERIALS AND METHODS:Forty rabbits were randomly divided into five groups of eight: normal control,...

journal_title：European review for medical and pharmacological sciences

authors： Xue L,Zhu XH,Yang XF,Bao XC,Gao XQ,Qiu YH,Wu Z,Ji XP,Li HW

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to evaluate the effect of 5-fluorouracil mobilized bone marrow regenerative cells (BMRCs) transplantation on brain injury following focal cerebral ischemia and to explore the mechanisms. MATERIALS AND METHODS:Male Sprague-Dawley rats were subjected to middle cerebral artery occlusio...

journal_title：European review for medical and pharmacological sciences

authors： Xu FF,Liu XL,Li M,Yang B,Liao H,Xiao LH,Xu ZP

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVE:Chemoresistance is the principal reason for poor survival and disease recurrence in osteosarcoma patients. Survivin, a family member of the inhibitor of apoptosis proteins, plays an important role in inhibition of apoptosis. Survivin is expressed in a vast majority of human cancers, which is often correlated ...

journal_title：European review for medical and pharmacological sciences

authors： Gao JZ,Chen FH,Wang L,Wei H,Meng SL

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVE:Trauma of the zygomaticomaxillary complex constitutes 45% of all midface fractures. In the author's medical unit, the proportion is 40% of all fractures of the facial skeleton. Most zygomaticomaxillary complex fractures can be treated via local incisions, however; multiple, comminuted and late fractures requi...

journal_title：European review for medical and pharmacological sciences

authors： Zhuang QW,Zhang XP,Wang X,Zhang J,Li ZP,Si YM,Meng J

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVE:To investigate the association between serum uric acid levels and the risk of incident atrial fibrillation in patients after coronary artery bypass graft (cABG) operation. PATIENTS AND METHODS:A total of 174 patients undergoing nonemergency coronary artery bypass graft operation were included in the study. P...

journal_title：European review for medical and pharmacological sciences

authors： Memetoglu ME,Kehlibar T,Yılmaz M,Günay R,Arslan Y,Tuygun A,Kocaaslan C,Çoskun G,Ketenci B,Güney MR,Demirtas M

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVE:Bone marrow-derived mesenchymal stem cells (MSCs) can serve as a vehicle for gene therapy. FGF2 (basic fibroblast growth factor) is a multifunctional growth factor and exhibits diverse function in different cell types, it also has pleiotropic effects in different tissues and organs, including potent angiogeni...

journal_title：European review for medical and pharmacological sciences

authors： Zhao YF,Luo YM,Xiong W,Ding W,Li YR,Zhao W,Zeng HZ,Gao HC,Wu XL

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVE:To determine the mRNA and protein expression, and methylation levels of the Klotho in lens epithelial cells (LECs) of normal transparent lenses and age-related cataracts (ARCs), and to explore the role of epigenetic changes of the Klotho gene in regulating the development of ARCs. PATIENTS AND METHODS:A tota...

journal_title：European review for medical and pharmacological sciences

authors： Jin SL,Zhang Y,Chen ZH,Qian DW,Qine YJ,Yongjie Q,He SK,Guo HK

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVE:To evaluate the recurrent ischemic events and risk factors in patients with symptomatic intracranial artery stenosis. PATIENTS AND METHODS:Patients with acute cerebral infarction or transient ischemia attach (TIA) and intracranial arterial stenosis confirmed through CTA examination, were enrolled from the De...

journal_title：European review for medical and pharmacological sciences

authors： Wang PQ,Liu JJ,Wang AP,Zhang GB,Cao ZH,Wang P,Zhou PY

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVE:Wilms tumor gene 1 (WT1) has been identified as an independent risk prognostic factor in acute leukemia. However, there exists a controversy that WT1 as a marker for minimal residual disease (MRD) monitoring in acute leukemias. We detected WT1-RNA transcript level to estimate the diagnostic value of monitorin...

journal_title：European review for medical and pharmacological sciences

authors： Zhang R,Yang JY,Sun HQ,Jia H,Liao J,Shi YJ,Li G

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVE:To explore the clinical efficacy of aneurysm embolization and cerebrospinal fluid (CSF) replacement in the treatment of aneurysmal subarachnoid hemorrhage (SAH). PATIENTS AND METHODS:Seventy-nine patients with grade III-IV aneurysmal subarachnoid hemorrhage, who were treated in the hospital from Jan. 2012 to...

journal_title：European review for medical and pharmacological sciences

authors： Ding W,Gao N,Li MX,Ding LJ,Li FF,Mou L

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVE:The precise etiology of inflammatory bowel diseases (IBDs) is still unknown although dysregulation of apoptosis likely plays an important role in this pathogenesis. However, the significance of mucosal T-cell apoptosis in ulcerative colitis (UC) is unclear. In the present work we investigated the role of TNF-...

journal_title：European review for medical and pharmacological sciences

authors： Hu D,Xia SL,Shao XX,Yu LQ,Lin XX,Guo M,Lin XQ,Jiang Y

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVE:Postpartum hemorrhage (PPH) is one of the major preventable causes of maternal death in developing countries. Although the non-parenteral use of misoprostol is a big advantage especially in home births, its benefits in prevention of PPH is still debating. We aimed to assess the effect and side-effects of prop...

journal_title：European review for medical and pharmacological sciences

authors： Uncu Y,Karahasan M,Uyaniklar Ö,Uncu G

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVE:Mesenchymal stem cells are a population of pluripotent cells that can differentiate into epidermal-like cells under certain conditions. Wnt3a can promote the proliferation and differentiation of stem cells. However, the role of Wnt3a in the differentiation of human umbilical cord mesenchymal stem cells (hUCMS...

journal_title：European review for medical and pharmacological sciences

authors： Sun TJ,Tao R,Han YQ,Xu G,Liu J,Han YF

更新日期：2015-01-01 00:00:00

abstract：:Protein kinase A (PKA) phosphorylates and activates cAMP response element-binding protein (CREB), which then binds to CRE domain on DNA and in turn activates genes involved in the process of learning and memorization. It has been demonstrated that CREB is involve in the learning and memory deficits that are caused by ...

journal_title：European review for medical and pharmacological sciences

authors： Peng S,Yang X,Liu GJ,Zhang XQ,Wang GL,Sun HY

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVE:Platelet hyper-reactivity is one of the most important causes of accelerated atherosclerosis and increased risk of thrombotic vascular events associated with type 2 diabetes mellitus (T2DM). This study aimed to investigate the effects of different add-on anti-diabetic therapies on platelet function in T2DM pa...

journal_title：European review for medical and pharmacological sciences

authors： Xiao CC,Ren A,Yang J,Ye SD,Xing XN,Li SM,Chen C,Chen RP

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVE:To investigate the effect of recombinant human p53 adenovirus injection combined with paclitaxel on human cervical cancer HeLa cell proliferation, apoptosis and expression of vascular endothelial growth factor (VEGF). MATERIALS AND METHODS:Detection of effects of paclitaxel, rAd-p53, and drug combination on ...

journal_title：European review for medical and pharmacological sciences

authors： Liu YG,Zheng XL,Liu FM

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVE:With improvement in methods, mortality after duodeno-cefalo pancreatectomy (DCP) has decreased to 5% even if complication rate is still high (30-50%). The pancreatic fistula still occurs in 25-50% of cases. Various methods of treating pancreatic stump have been proposed aimed to improve this rate. PATIENTS A...

journal_title：European review for medical and pharmacological sciences

authors： Bentivegna F,Cortese V,Bentivegna S,Cardì F,Di Mattia P,Barbera G,Borzì AM,Zanghì G

更新日期：2014-12-01 00:00:00

abstract：OBJECTIVE:Data regarding the cerebral atherosclerotic stenosis (CAS) and incidence of stroke are conflicting. The number of stroke patients is more than three times that from coronary heart disease in China. The main aim of this report is to review the current status of intracranial and extracranial atherosclerotic ste...

journal_title：European review for medical and pharmacological sciences

authors： Liu CY,Chen CQ

更新日期：2014-11-01 00:00:00

abstract：OBJECTIVE:The objective of this study was to evaluate the relationship between disease severity and biochemical parameters such as pentraxin3, CRP, fetuin-A, insulin and HOMA-IR levels in patients with psoriasis. PATIENTS AND METHODS:This study included 58 patients with psoriasis and 30 healthy controls admitted to An...

journal_title：European review for medical and pharmacological sciences

authors： Uysal S,Yılmaz FM,Karatoprak K,Artüz F,Cumbul NU

更新日期：2014-11-01 00:00:00

abstract：OBJECTIVE:To analyze the clinical values of three commonly used scoring systems including Wells score, revised Geneva score and Pisa score in predicting pulmonary thromboembolism (PTE) in Xining area. PATIENTS AND METHODS:A total of 67 patients who had received CT pulmonary angiography (CTPA) in Qinghai Provincial Peo...

journal_title：European review for medical and pharmacological sciences

authors： Gu YH,Zhao Z

更新日期：2014-11-01 00:00:00

abstract：AIM:The aim of this study was to screen miRNAs related to different subtypes of breast cancer and their target genes to identify new markers of tumor subtype. MATERIALS AND METHODS:The miRNA expression profiles of breast cancer GSE38867 including 7 ductal carcinoma in situ breast (DCIS) cancer samples, 7 invasive brea...

journal_title：European review for medical and pharmacological sciences

authors： Sun EH,Zhou Q,Liu KS,Wei W,Wang CM,Liu XF,Lu C,Ma DY

更新日期：2014-10-01 00:00:00

abstract：OBJECTIVE:Staging in rectal carcinoma is important for planning treatment. Preoperative staging and treatment strategies have changed along with improvements in imaging techniques. The aim of this work is to evaluate the accuracy of endorectal ultrasound (ERUS) in rectal cancers, especially in low rectal cancers and st...

journal_title：European review for medical and pharmacological sciences

authors： Kuran S,Ozin Y,Nessar G,Turhan N,Sasmaz N

更新日期：2014-10-01 00:00:00

abstract：OBJECTIVE:Biofilms are microbial communities consisting of bacteria, extremely capable to self-reproduce on biological surfaces, causing infections. Frequently, these biofilms are resistant to classical antibacterial treatments and host immune response. Thus, new adjuvant molecules are mandatory in clinical practice. N...

journal_title：European review for medical and pharmacological sciences

authors： Dinicola S,De Grazia S,Carlomagno G,Pintucci JP

更新日期：2014-10-01 00:00:00

abstract：OBJECTIVE:To observe the serum inflammatory and coagulation factors changes and clinical significance following carotid artery stenting. PATIENTS AND METHODS:The expressions of serum inflammatory factors including IL-2, IL-6, IL-8, sICAM-1, hs-CRP, and TNF-α and serum coagulation factors including prothrombin time (PT...

journal_title：European review for medical and pharmacological sciences

authors： Jia XJ,Fang SZ,Zhu QF,Xie RT,Liu ZY

更新日期：2014-10-01 00:00:00

abstract：:Atherosclerosis, the hardening of arteries under oxidative stress is related to oxidative changes of low density lipoproteins (LDL). The antioxidants prevent the formation of oxidized LDL during atherogenesis. Perhaps more than one mechanism is involved in the atherosclerosis disease where LDL is oxidized in all the c...

journal_title：European review for medical and pharmacological sciences

authors： Zhang PY,Xu X,Li XC

更新日期：2014-10-01 00:00:00

abstract：OBJECTIVE:The underlying inflammation of endometrium may impede normal implantation of placenta during pregnancy. Our objective is to show cervical colonization of ureaplasma and/or mycoplasma as a marker of endometritis in pregnancies complicated with placenta previa that can be a risk factor for placenta accreta and ...

journal_title：European review for medical and pharmacological sciences

authors： Aydogan P,Kahyaoglu S,Saygan S,Kaymak O,Mollamahmutoglu L,Danisman N

更新日期：2014-08-01 00:00:00

abstract：OBJECTIVE:Posttraumatic stress disorder (PTSD) is an adverse psychological response to traumatic events. Microarray technology for large-scale gene expression analysis facilitates the identification of signatures that underlie the pathogenesis of PTSD. Previous studies mostly used variance/regression analysis without c...

journal_title：European review for medical and pharmacological sciences

authors： Dong K,Zhang F,Zhu W,Wang Z,Wang G

更新日期：2014-08-01 00:00:00